Rabbit Polyclonal Antibody to RHOC
货号:
P34316
别名:
Rho-related GTP-binding protein RhoC, Rho cDNA clone 9, h9, RHOC, ARH9, ARHC
应用:
WB
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
P08134
规格:
目录价
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Description |
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This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Specification |
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Aliases | Rho-related GTP-binding protein RhoC, Rho cDNA clone 9, h9, RHOC, ARH9, ARHC |
Entrez GeneID | 389 |
Swissprot | P08134 |
WB Predicted band size | 22.0kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | This RHOC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the C-terminal region of human RHOC. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/2000 |