Mouse Monoclonal Antibody to CD127
货号：
31599
别名：
IL7R; ILRA; IL7RA; CDW127; IL-7R-alpha
应用：
WB,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P16871
规格：
目录价
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Description |
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The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. |
References |
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| 1.J Clin Immunol. 2017 Jan;37(1):42-50. 2.Blood. 2016 Jul 28;128(4):473-8. |
Specification |
|
|---|---|
| Aliases | IL7R; ILRA; IL7RA; CDW127; IL-7R-alpha |
| Entrez GeneID | 3575 |
| Swissprot | P16871 |
| clone | 3F5D9 |
| WB Predicted band size | 51.6kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD127 (AA: extra 21-239) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using CD127 mouse mAb against Hela (1), HL-60 (2), and U937 (3) cell lysate.
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Flow cytometric analysis of HL-60 cells using CD127 mouse mAb (green) and negative control (red).
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