Mouse Monoclonal Antibody to RIPK3
货号：
P34657
别名：
Receptor-interacting serine/threonine-protein kinase 3, 2.7.11.1, RIP-like protein kinase 3, Receptor-interacting protein 3, RIP-3, RIPK3, RIP3
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9Y572
规格：
目录价
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Description |
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Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production. |
Specification |
|
|---|---|
| Aliases | Receptor-interacting serine/threonine-protein kinase 3, 2.7.11.1, RIP-like protein kinase 3, Receptor-interacting protein 3, RIP-3, RIPK3, RIP3 |
| Entrez GeneID | 11035 |
| Swissprot | Q9Y572 |
| WB Predicted band size | 56.9kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This RIPK3 antibody is generated from a mouse immunized with a recombinate protein from the human region of human RIPK3. |
Application |
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|---|---|
| WB | 1/1000 |
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