Rabbit Polyclonal Antibody to NLRP6 (N-term)
货号：
P34678
别名：
NACHT, LRR and PYD domains-containing protein 6, Angiotensin II/vasopressin receptor, PYRIN-containing APAF1-like protein 5, NLRP6, NALP6, PYPAF5
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P59044
规格：
目录价
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Description |
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NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]). |
Specification |
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|---|---|
| Aliases | NACHT, LRR and PYD domains-containing protein 6, Angiotensin II/vasopressin receptor, PYRIN-containing APAF1-like protein 5, NLRP6, NALP6, PYPAF5 |
| Entrez GeneID | 171389 |
| Swissprot | P59044 |
| WB Predicted band size | 98.8kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This NLRP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the N-terminal region of human NLRP6. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/2000 |
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