Rabbit Polyclonal Antibody to TNIK(S764)
货号：
P34692
别名：
TRAF2 and NCK-interacting protein kinase, 2.7.11.1, TNIK, KIAA0551
应用：
WB
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q9UKE5
规格：
目录价
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Description |
|---|
Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322. |
Specification |
|
|---|---|
| Aliases | TRAF2 and NCK-interacting protein kinase, 2.7.11.1, TNIK, KIAA0551 |
| Entrez GeneID | 23043 |
| Swissprot | Q9UKE5 |
| WB Predicted band size | 154.9kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This TNIK(S764) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human TNIK(S764). |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500 |
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