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Mouse Monoclonal Antibody to PURB
货号: P34754
别名: Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB
应用: WB
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q96QR8
规格:
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Description

Has capacity to bind repeated elements in single- stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine- rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity).

Specification

Aliases Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB
Entrez GeneID 5814
Swissprot Q96QR8
WB Predicted band size 33.2kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen This PURB antibody is generated from a mouse immunized with a recombiant protein of human PURB.

Application

WB 1/8000
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