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Mouse Monoclonal Antibody to MMP14
货号: P34913
别名: Matrix metalloproteinase-14, MMP-14, MMP-X1, Membrane-type matrix metalloproteinase 1, MT-MMP 1, MTMMP1, Membrane-type-1 matrix metalloproteinase, MT1-MMP, MT1MMP, MMP14
应用: WB
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: P50281
规格:
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Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Specification

Aliases Matrix metalloproteinase-14, MMP-14, MMP-X1, Membrane-type matrix metalloproteinase 1, MT-MMP 1, MTMMP1, Membrane-type-1 matrix metalloproteinase, MT1-MMP, MT1MMP, MMP14
Entrez GeneID 4323
Swissprot P50281
WB Predicted band size 65.9kDa
Host/Isotype Mouse IgM
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen This MMP14 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human MMP14.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/1000
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