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Rabbit Polyclonal Antibody to Connexin 50 (N-term)
货号: P35065
别名: Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: P48165
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Description

GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.

Specification

Aliases Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8
Entrez GeneID 2703
Swissprot P48165
WB Predicted band size 48.2kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This Connexin 50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-130 amino acids from the N-terminal region of human Connexin 50.
Formulation Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) .

Application

WB 1/1000
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