Rabbit Polyclonal Antibody to MEK2(Phospho-Thr394)
货号:
P40008
别名:
ERK activator kinase 2; MAP kinase kinase 2; MAP2K2; MAPK/ERK kinase 2; MAPKK 2
应用:
WB,IHC,IF
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P36507
规格:
目录价
在线咨询
Description |
---|
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases. |
References |
---|
Crews C M, et al. (1992) Science. 258:478-480.Alessi D R, et al. (1994) EMBO J. 13:1610-1619.Rosen L B, et al. (1994) Neuron. 12:1207-1221.Cowley S, et al. (1994) Cell. 77:841-852. |
Specification |
|
---|---|
Aliases | ERK activator kinase 2; MAP kinase kinase 2; MAP2K2; MAPK/ERK kinase 2; MAPKK 2 |
Entrez GeneID | 5605; |
Swissprot | P36507 |
WB Predicted band size | 44kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Peptide sequence around phosphorylation site of threonine 394 (P-G-T(p)-P-T) derived from Human MEK-2. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
IF | 1/100-1/200 |
Product Image
-
Western blot analysis of extracts from HepG2 and Hela cells untreated or treated with UV using MEK-2(Phospho-Thr394) Antibody P40008.
-
Immunofluorescence staining of methanol-fixed Hela cells using MEK-2(Phospho-Thr394) Antibody P40008.
-
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MEK-2(Phospho-Thr394) Antibody P40008(left) or the same antibody preincubated with blocking peptide(right).