Rabbit Polyclonal Antibody to Elk-1(Phospho-Ser383)
货号:
P40004
别名:
ELK1; ETS-domain protein Elk-1;
应用:
WB,IHC
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
P19419
规格:
目录价
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Description |
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Elk-1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. lternatively spliced transcript variants encoding the same protein have been found for this gene. |
References |
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Xing J, et al. (1996) Science. 273(5277): 959-963.Janknecht R, et al. (1993) EMBO J. 12(13): 5097-5104.Marais R, et al. (1993) Cell 73: 381-393.Kortenjann M, et al. (1994) Mol Cell Biol. 14: 4815-4824.Cavigelli M, et al. (1995) EMBO J. 14: 5957-5964. |
Specification |
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Aliases | ELK1; ETS-domain protein Elk-1; |
Entrez GeneID | 2002; |
Swissprot | P19419 |
WB Predicted band size | 47kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around phosphorylation site of serine 383 (T-L-S(p)-P-I) derived from Human Elk-1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from HT29 cells untreated or treated with UV using Elk-1(Phospho-Ser383) Antibody P40004.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Elk-1(Phospho-Ser383) Antibody P40004(left) or the same antibody preincubated with blocking peptide(right).