Rabbit Polyclonal Antibody to ICAM-1(Phospho-Tyr512)
货号：
P40082
别名：
ICA1; ICAM1;
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P05362
规格：
目录价
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Description |
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ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
References |
|---|
| Greenwood J, et al. (2003) J Immunol; 171(4):2099-2108. Zhou Z, et al. (2005) Eur J Pharmacol; 513(1-2):1-8. Chen YH, et al. (2001) J Cell Biochem; 82(3):512-521 |
Specification |
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|---|---|
| Aliases | ICA1; ICAM1; |
| Entrez GeneID | 3383; |
| Swissprot | P05362 |
| WB Predicted band size | 89 92kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 512 (K-K-Y(p)-R-L) derived from Human ICAM-1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
Product Image
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Western blot analysis of extracts from HUVEC cells using ICAM-1(Phospho-Tyr512) Antibody P40082(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).
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Western blot analysis of extracts from C2C12 cells, treated with starve or calf intestinal phosphatase (CIP), using ICAM-1 (Phospho-Tyr512) Antibody P40082.
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