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Rabbit Polyclonal Antibody to BAD(Phospho-Ser155)
货号: P40068
别名: Bbc2; AI325008
应用: WB,IHC
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q61337
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Description

Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

References

Schurmann A., Mooney A.F., Sanders L.C., Sells M.A., Wang H.G., Reed J.C., Bokoch G.M.Mol. Cell. Biol. 20:453-461(2000) Jakobi R., Moertl E., Koeppel M.A.J. Biol. Chem. 276:16624-16634(2001)

Specification

Aliases Bbc2; AI325008
Entrez GeneID 12015;
Swissprot Q61337
WB Predicted band size 23kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around phosphorylation site of serine 155(R-M-S(p)-D-E) derived from Human BAD.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
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