Rabbit Polyclonal Antibody to EGFR(Phospho-Ser1070)
货号：
P40079
别名：
ERBB1; Receptor protein-tyrosine kinase ErbB-1; kinase EGFR
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P00533
规格：
目录价
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Description |
|---|
Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin. |
References |
|---|
| Feinmesser RL,et al. (1999) J Biol Chem; 274(23): 16168-73.Gamou S,et al. (1995) FEBS Lett; 357(2): 161-4.Gamou S, et al. (1994) J Cell Physiol; 158(1): 151-9.Heisermann GJ, et al. (1988) J Biol Chem; 263(26): 13152-8. |
Specification |
|
|---|---|
| Aliases | ERBB1; Receptor protein-tyrosine kinase ErbB-1; kinase EGFR |
| Entrez GeneID | 1956; |
| Swissprot | P00533 |
| WB Predicted band size | 175kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of serine 1070 (R-Y-S(p)-S-D) derived from Human EGFR. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from HUVEC cells untreated or treated with EGF using EGFR(Phospho-Ser1070) Antibody P40079.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using EGFR(Phospho-Ser1070) Antibody P40079(left) or the same antibody preincubated with blocking peptide(right).
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