Rabbit Polyclonal Antibody to HER2(Phospho-Tyr1248)
货号:
P40078
别名:
C-erbB-2; ErbB2;
应用:
WB,IHC,IF
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
P04626
规格:
目录价
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Description |
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Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-a and amphiregulin. |
References |
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Yuan,Lu Qian ,Ming Shi, et al. (2008) HER2-dependent MMP-7 expression is mediated by activated STAT3 Guogang Cellular Signalling, 20:1284 |
Specification |
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Aliases | C-erbB-2; ErbB2; |
Entrez GeneID | 2064; |
Swissprot | P04626 |
WB Predicted band size | 185kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around phosphorylation site of tyrosine1248 (P-E-Y(p)-L-G) derived from Human HER2. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from HepG2 cells treated with PMA and MCF cells treated with EGF, using HER2 (Phospho-Tyr1248) Antibody P40078.
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Immunofluorescence staining of methanol-fixed MCF7 cells using HER2(Phospho-Tyr1248) Antibody P40078.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HER2 (Phospho-Tyr1248) Antibody P40078 (left) or the same antibody preincubated with blocking peptide (right).
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Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using HER2 (Phospho-Tyr1248) Antibody P40078.