Rabbit Polyclonal Antibody to p27Kip1(Phospho-Thr187)
货号：
P40195
别名：
CDKN1B; CDN1B; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; KIP1
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P46527
规格：
目录价
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Description |
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Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events. |
References |
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| Eguchi H, et al. (2003) Cancer Res; 63(15): 4739-46Le XF, et al. (2003) J Biol Chem;Connor MK, et al. (2003) |
Specification |
|
|---|---|
| Aliases | CDKN1B; CDN1B; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; KIP1 |
| Entrez GeneID | 1027; |
| Swissprot | P46527 |
| WB Predicted band size | 27kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of threonine 187 (E-Q-T(p)-P-K) derived from Human p27Kip1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from Hela cells untreated or treated with EGF, IFN-a using p27Kip1(Phospho-Thr187) Antibody P40195.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p27Kip1(Phospho-Thr187) Antibody P40195(left) or the same antibody preincubated with blocking peptide(right).
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