Rabbit Polyclonal Antibody to Zap-70(Phospho-Tyr493)
货号：
P40154
别名：
70 kDa zeta-associated protein; SRK; Syk-related tyrosine kinase; ZA70; ZAP-70
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P43403
规格：
目录价
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Description |
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Plays a role in T-cell development and lymphocyte activation. Essential for TCR-mediated IL-2 production. Isoform 1 induces TCR-mediated signal transduction, isoform 2 does not. |
References |
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| Chan AC, et al. (1995) EMBO J; 14(11): 2499-2508Kong G, et al. (1996) Mol Cell Biol; 16(9): 5026-5035Salomon AR, et al. (2003)Proc Natl Acad Sci U S A; 100(2): 443-448 |
Specification |
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|---|---|
| Aliases | 70 kDa zeta-associated protein; SRK; Syk-related tyrosine kinase; ZA70; ZAP-70 |
| Entrez GeneID | 7535; |
| Swissprot | P43403 |
| WB Predicted band size | 70kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 493 (S-Y-Y(p)-T-A) derived from Human Zap-70. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from JK cells untreated or treated with anisomycin using Zap-70(Phospho-Tyr493) Antibody P40154.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Zap-70(Phospho-Tyr493) Antibody P40154(left) or the same antibody preincubated with blocking peptide(right).
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