Rabbit Polyclonal Antibody to Zap-70(Phospho-Tyr319)
货号：
P40153
别名：
SRK, STD, TZK, STCD, ZAP-70
应用：
WB,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P43403
规格：
目录价
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Description |
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Plays a role in T-cell development and lymphocyte activation. Essential for TCR-mediated IL-2 production. Isoform 1 induces TCR-mediated signal transduction, isoform 2 does not. |
References |
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| Salomon AR, et al. (2003) Proc Natl Acad Sci U S A; 100(2): 443-448 Ku GM, et al. (2001) EMBO J; 20(3): 457-465 Tang J, et al. (1999) Proc Natl Acad Sci U S A; 96(17): 9775-9780 Zhao Q, et al. (1996) Mol Cell Biol; 16(12): 6765-6774 Williams BL, et al. (1999) EMBO J; 18(7): 1832-1844 Adjali O, et al. (2005) J Clin Invest; 115(8): 2287-2295. |
Specification |
|
|---|---|
| Aliases | SRK, STD, TZK, STCD, ZAP-70 |
| Entrez GeneID | 7535; |
| Swissprot | P43403 |
| WB Predicted band size | 70kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 319 (S-P-Y(p)-S-D) derived from Human Zap-70. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from Jurkat cells using Zap-70(Phospho-Tyr319) Antibody P40153(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).
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Western blot analysis of extracts from HL60 cells, treated with calf intestinal phosphatase (CIP), using Zap-70 (Phospho-Tyr319) Antibody P40153.
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Immunofluorescence staining of methanol-fixed Hela cells using Zap-70(Phospho-Tyr319) Antibody P40153.
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