Rabbit Polyclonal Antibody to HDAC2(Phospho-Ser394)
货号：
P40182
别名：
HD2
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q92769
规格：
目录价
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Description |
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Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes |
References |
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| Tsai SC, et al.(2002)J Biol Chem; 277(35): 31826-33 |
Specification |
|
|---|---|
| Aliases | HD2 |
| Entrez GeneID | 3066; |
| Swissprot | Q92769 |
| WB Predicted band size | 60kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of serine 394 (E-D-S(p)-G-D) derived from Human HDAC2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from 293 cells untreated or treated with EGF using HDAC2(Phospho-Ser394) Antibody P40182.
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Western blot analysis of extracts from HepG2 cells, treated with calf intestinal phosphatase (CIP), using HDAC2 (Phospho-Ser394) Antibody P40182.
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Immunofluorescence staining of methanol-fixed Hela cells showing nuclear staining using HDAC2(Phospho-Ser394) Antibody P40182.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HDAC2(Phospho-Ser394) Antibody P40182(left) or the same antibody preincubated with blocking peptide(right).
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