Rabbit Polyclonal Antibody to Smad3(Phospho-Ser425)
货号：
P40293
别名：
JV15-2; MAD-3; MADH3; Mad3; Mothers against DPP homolog 3
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P84022
规格：
目录价
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Description |
|---|
Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. |
References |
|---|
| Shi W, et al. J Cell Sci. 2007 Apr 1;120(Pt 7):1216-24Seong HA, et al. J Biol Chem. 2007 Apr 20;282(16):12272-89Wordinger RJ, et al. Invest Ophthalmol Vis Sci. 2007 Mar;48(3):1191-200LeClair RJ, et al. Circ Res. 2007 Mar 30;100(6):826-33 |
Specification |
|
|---|---|
| Aliases | JV15-2; MAD-3; MADH3; Mad3; Mothers against DPP homolog 3 |
| Entrez GeneID | 4088; |
| Swissprot | P84022 |
| WB Predicted band size | 52kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of serine 425 (C-S-S-V-S(p)) derived from Human Smad3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from Hela cells untreated or treated with EGF using Smad3(Phospho-Ser425) Antibody P40293.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Smad3(Phospho-Ser425) Antibody P40293(left) or the same antibody preincubated with blocking peptide(right).
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