Rabbit Polyclonal Antibody to SHP-2(Phospho-Tyr542)
货号：
P40288
别名：
PTN11; PTP-1D; PTP-2C; PTP2C; PTPN11
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q06124
规格：
目录价
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Description |
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Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. |
References |
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| Ferjoux G, et al. (2003) Mol Biol Cell. 2003; 14(9): 3911-3928. Shi ZQ, et al. (2000) Mol Cell Biol. 20(5): 1526-1536. Li C, Friedman JM. (1999) Proc Natl Acad Sci U S A ; 96(17): 9677-9682 Manes S, et al. (1999) Mol Cell Biol. 19(4): 3125-3135. Oh ES, et al. (1999) Mol Cell Biol; 19(4): 3205-3215. |
Specification |
|
|---|---|
| Aliases | PTN11; PTP-1D; PTP-2C; PTP2C; PTPN11 |
| Entrez GeneID | 5781; |
| Swissprot | Q06124 |
| WB Predicted band size | 72kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 542 (H-E-Y(p)-T-N) derived from Human SHP-2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from 293 cells untreated or treated with starvation using SHP-2(Phospho-Tyr542) Antibody P40288.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SHP-2(Phospho-Tyr542) Antibody P40288(left) or the same antibody preincubated with blocking peptide(right).
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