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Rabbit Polyclonal Antibody to Cyclin E1(phospho-Thr395)
货号: P40325
别名: CCNE; CCNE1;
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: P24864
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Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition.

References

Won K.A., Reed S.I.EMBO J. 15:4182-4193(1996)Welcker M., Singer J., Loeb K.R., Grim J., Bloecher A., Mol. Cell 12:381-392(2003)

Specification

Aliases CCNE; CCNE1;
Entrez GeneID 898;
Swissprot P24864
WB Predicted band size 48kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around phosphorylation site of threonine 395 (L-L-T(p)-P-P)derived from Human Cyclin E1
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
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