Rabbit Polyclonal Antibody to STAT2(phospho-Tyr690)
货号：
P40320
别名：
P113; ISGF-3; STAT113; MGC59816;
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P52630
规格：
目录价
在线咨询
Description |
|---|
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has |
References |
|---|
| been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-a response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. Fu X.Y,et al.Proc. Natl. Acad. Sci. U.S.A. 89:7840-7843(1992)Yan R,et al. Nucleic Acids Res. 23:459-463(1995)Fu X.Y.Cell 70:323-335(1992) Sugiyama T,et al.FEBS Lett. 381:191-194(1996) |
Specification |
|
|---|---|
| Aliases | P113; ISGF-3; STAT113; MGC59816; |
| Entrez GeneID | 6773; |
| Swissprot | P52630 |
| WB Predicted band size | 113kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 690 (R-K-Y(p)-L-K)derived from Human Stat2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
鄂公网安备42018502007531号
