Rabbit Polyclonal Antibody to DLC1 (Phospho-Ser986)
货号：
P40356
别名：
ARHGAP7, KIAA1723, STARD12
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q96QB1
规格：
目录价
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Description |
|---|
Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality. |
Specification |
|
|---|---|
| Aliases | ARHGAP7, KIAA1723, STARD12 |
| Entrez GeneID | 10395; |
| Swissprot | Q96QB1 |
| WB Predicted band size | 171kDa 114kDa 123kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of serine 986 (R-D-S(p)-G-V) derived from Human DLC1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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