Rabbit Polyclonal Antibody to p13Cas (Phospho-Tyr410)
货号：
P40373
别名：
BCAR1; CRKAS; CRK-ASSOCIATED SUBSTRATE;
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P56945
规格：
目录价
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Description |
|---|
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.Katarzyna Modzelewska, J. Biol. Chem., Dec 2006; 281: 37527 - 37535Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006; 291: H2857 - H2863Sangkil Nam, Cancer Res., Oct 2005; 65: 9185 - 9189Norikazu Yamana, Mol. Cell. Biol., Sep 2006; 26: 6844 - 6 |
Specification |
|
|---|---|
| Aliases | BCAR1; CRKAS; CRK-ASSOCIATED SUBSTRATE; |
| Entrez GeneID | 9564; |
| Swissprot | P56945 |
| WB Predicted band size | 130kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from Human p130 Cas . |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from K562 cells (Lane 2) and 3T3 cells (Lane 3), using P130 Cas(Phospho-Tyr410) Antibody P40373. The lane on the left is treated with antigen-specific peptide.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using p130 Cas (Phospho-Tyr410) antibody P40373 (left)or the same antibody preincubated with blocking peptide (right).
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