Rabbit Polyclonal Antibody to Bax (Phospho-Thr167)
货号：
P40392
别名：
BAXA; Apoptosis regulator BAX; membrane isoform alpha; Bcl2-associated X protein;
应用：
IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q07812
规格：
目录价
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Description |
|---|
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.Francesca Andriani. J Natl Cancer Inst, Sep 2001; 93: 1314 - 1324. H Martinez-Valdez. J. Exp. Med., Mar 1996; 183: 971. Joslyn K. Brunelle. J. Biol. Chem., Feb 2004; 279: 4305 - 4312 |
Specification |
|
|---|---|
| Aliases | BAXA; Apoptosis regulator BAX; membrane isoform alpha; Bcl2-associated X protein; |
| Entrez GeneID | 581; |
| Swissprot | Q07812 |
| WB Predicted band size | 21kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of threonine167 (P-G-T(p)-P-T) derived from Human Bax. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| IF | 1/100-1/200 |
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