Rabbit Polyclonal Antibody to CCR5 (Phospho-Ser349)
货号：
P40372
别名：
C-C CKR-5; CKR5; CHEMR13; CMKBR5; CCR-5
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P51681
规格：
目录价
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Description |
|---|
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.Martin Oppermann, J. Biol. Chem., Mar 1999; 274: 8875Beatrix Pollok-Kopp, J. Biol. Chem., Jan 2003; 278: 2190 - 2198Ramtin Rahbar, J. Virol., Jul 2006; 80: 7245 - 7259H Olbrich, J. Leukoc. Biol., Mar 1999; 65: 281 |
Specification |
|
|---|---|
| Aliases | C-C CKR-5; CKR5; CHEMR13; CMKBR5; CCR-5 |
| Entrez GeneID | 1234; |
| Swissprot | P51681 |
| WB Predicted band size | 40kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of Serine 349 (E-I-S(p)-V-G) derived from Human CCR5. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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