Rabbit Polyclonal Antibody to MLC2 (Phospho-Ser15)
货号：
P40354
别名：
CMH10, MFM12, MLC-2, MLC-2s/v, MLC-2v, MLC2
应用：
WB,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P10916
规格：
目录价
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Description |
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Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. |
References |
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| 1) Xia, Y. et al. c-Jun downregulation by HDAC3-dependent transcriptionalrepression promotes osmotic stress-induced cell apoptosis. Mol. Cell 25,219–232 (2007). 2)Vander Heiden, M. G. et al. Evidence for an alternative glycolytic pathway inrapidly proliferating cells. Science 329, 1492–1499 (2010). 3) Fang, D. et al. Phosphorylation of beta-catenin by AKT promotes beta-catenintranscriptional activity. J. Biol. Chem. 282, 11221–11229 (2007). |
Specification |
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|---|---|
| Aliases | CMH10, MFM12, MLC-2, MLC-2s/v, MLC-2v, MLC2 |
| Entrez GeneID | 4633; |
| Swissprot | P10916 |
| WB Predicted band size | 20kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of serine 15 (A-N-S(p)-N-V) derived from Human MLC2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/1000 |
| IF | 1/100-1/200 |
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