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Rabbit Polyclonal Antibody to PEA-15 (Phospho-Ser104)
货号: P40389
别名: PE15; PEA15; PED;
应用: WB,IHC
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q15121
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Description

Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.Estelles A., J. Biol. Chem. 271:14800-14806(1996)Condorelli G., EMBO J. 17:3858-3866(1998)Wolford J.K., Gene 241:143-148(2000)

Specification

Aliases PE15; PEA15; PED;
Entrez GeneID 8682;
Swissprot Q15121
WB Predicted band size 19kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around phosphorylation site of Serine 104(I-P-S(p)-A-K) derived from Human PEA-15.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
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