Rabbit Polyclonal Antibody to PEA-15 (Phospho-Ser104)
货号:
P40389
别名:
PE15; PEA15; PED;
应用:
WB,IHC
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q15121
规格:
目录价
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Description |
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Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.Estelles A., J. Biol. Chem. 271:14800-14806(1996)Condorelli G., EMBO J. 17:3858-3866(1998)Wolford J.K., Gene 241:143-148(2000) |
Specification |
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Aliases | PE15; PEA15; PED; |
Entrez GeneID | 8682; |
Swissprot | Q15121 |
WB Predicted band size | 19kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around phosphorylation site of Serine 104(I-P-S(p)-A-K) derived from Human PEA-15. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from COS cells treated with TNF using PEA-15 (Phospho-Ser104) Antibody P40389.The lane on the right is treated with the antigen-specific peptide.
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Immunohistochemical analysis of paraffin-embedded human heart tissue using PEA-15 (Phospho-Ser104) antibody P40389 (left)or the same antibody preincubated with blocking peptide (right).