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Rabbit Polyclonal Antibody to CD32 (Phospho-Tyr292)
货号: P40386
别名: CD32; FCG2; FCG2B,; LY-17; CDW32
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: P31994
规格:
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Description

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.Stuart S.G., EMBO J. 8:3657-3666(1989)Brooks D.G., J. Exp. Med. 170:1369-1385(1989)Engelhardt W., Eur. J. Immunol. 20:1367-1377(1990)

Specification

Aliases CD32; FCG2; FCG2B,; LY-17; CDW32
Entrez GeneID 2213;
Swissprot P31994
WB Predicted band size 32kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
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