Rabbit Polyclonal Antibody to CD32 (Phospho-Tyr292)
货号:
P40386
别名:
CD32; FCG2; FCG2B,; LY-17; CDW32
应用:
WB
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P31994
规格:
目录价
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Description |
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Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.Stuart S.G., EMBO J. 8:3657-3666(1989)Brooks D.G., J. Exp. Med. 170:1369-1385(1989)Engelhardt W., Eur. J. Immunol. 20:1367-1377(1990) |
Specification |
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Aliases | CD32; FCG2; FCG2B,; LY-17; CDW32 |
Entrez GeneID | 2213; |
Swissprot | P31994 |
WB Predicted band size | 32kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |