Rabbit Polyclonal Antibody to CK-1α (Phospho-Tyr294)
货号：
P40432
别名：
KC1A; CKI-alpha; CSNK1A1; alpha isoform; Casein kinase I
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P48729
规格：
目录价
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Description |
|---|
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.Tapia C., FEBS Lett. 349:307-312(1994)Fish K.J., J. Biol. Chem. 270:14875-14883(1995)Halleck A., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases |
Specification |
|
|---|---|
| Aliases | KC1A; CKI-alpha; CSNK1A1; alpha isoform; Casein kinase I |
| Entrez GeneID | 1452; |
| Swissprot | P48729 |
| WB Predicted band size | 37kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 294 (Y-D-Y(p)-T-F) derived from Human CK-1α. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from HT-29 cells treated with heat shock using CK-1α (Phospho-Tyr294) Antibody P40432.The lane on the right is treated with the antigen-specific peptide.
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Immunohistochemical analysis of paraffin-embedded human brain tissue using CK-1α (Phospho-Tyr294) antibody P40432 (left)or the same antibody preincubated with blocking peptide (right).
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