Rabbit Polyclonal Antibody to MYT1 (Phospho-Ser83)
货号：
P40448
别名：
PMYT1; PKMYT1; MYT1 kinase;
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q99640
规格：
目录价
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Description |
|---|
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.Booher R.N., J. Biol. Chem. 272:22300-22306(1997)Liu F., Mol. Cell. Biol. 17:571-583(1997)Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006) |
Specification |
|
|---|---|
| Aliases | PMYT1; PKMYT1; MYT1 kinase; |
| Entrez GeneID | 9088; |
| Swissprot | Q99640 |
| WB Predicted band size | 54kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of Serine 83(R-V-S(p)-F-R) derived from Human MYT1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| IHC | 1/50-1/100 |
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