Rabbit Polyclonal Antibody to ATF-2 (Phospho-Ser472)
货号：
P40485
别名：
Activating 2; ATF2; cAMP response element binding protein CRE- BP1; CREB2; HB16
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P15336
规格：
目录价
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Description |
|---|
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex. |
References |
|---|
| Maekawa T., EMBO J. 8:2023-2028(1989) Yang L., J. Immunol. 158:2522-2525(1997) Kara C.J., Mol. Cell. Biol. 10:1347-1357(1990). |
Specification |
|
|---|---|
| Aliases | Activating 2; ATF2; cAMP response element binding protein CRE- BP1; CREB2; HB16 |
| Entrez GeneID | 1386; |
| Swissprot | P15336 |
| WB Predicted band size | 54kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of Serine 472 (A-L-S(p)-Q-I) derived from Human ATF-2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| IHC | 1/50-1/100 |
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