Rabbit Polyclonal Antibody to MAP3K1 (Phospho-Thr1400)
货号:
P40441
别名:
M3K1; MAP3K1; MAPKKK1; MEKK1;
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q13233
规格:
目录价
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Description |
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Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway |
References |
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Schmutz J., Nature 431:268-274(2004) Xia Y., Genes Dev. 12:3369-3381(1998) Vinik B.S., Mamm. Genome 6:782-783(1995) |
Specification |
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Aliases | M3K1; MAP3K1; MAPKKK1; MEKK1; |
Entrez GeneID | 4214; |
Swissprot | Q13233 |
WB Predicted band size | 130kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Peptide sequence around phosphorylation site of threonine 1400(K-G-T(p)-G-A) derived from Human MAP3K1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from JK cells (Lane 2), using MAP3K1 (Phospho-Thr1400) Antibody P40441. The lane on the left is treated with antigen-specific peptide.
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Immunohistochemical analysis of paraffin-embedded human brain tissue using MAP3K1 (Phospho-Thr1400) antibody P40441 (left)or the same antibody preincubated with blocking peptide (right).