Rabbit Polyclonal Antibody to Cyclin C (Phospho-Ser275)
货号：
P40497
别名：
CG1C; cyclin C; SRB11;
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P24863
规格：
目录价
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Description |
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The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.Lew D.J., Cell 66:1197-1206(1991)Li H., Genomics 32:253-259(1996)Mungall A.J., Nature 425:805-811(2003) |
Specification |
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|---|---|
| Aliases | CG1C; cyclin C; SRB11; |
| Entrez GeneID | 892; |
| Swissprot | P24863 |
| WB Predicted band size | 37kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of Serine 275(N-G-S(p)-A-N) derived from Human Cyclin C. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from 3T3 cells (Lane 2), A549 cells (Lane 3) and Hela cells (Lane 4), using Cyclin C (Phospho-Ser275) Antibody P40497. The lane on the left is treated with antigen-specific peptide.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Cyclin C (Phospho-Ser275) antibody P40497 (left)or the same antibody preincubated with blocking peptide (right).
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