Rabbit Polyclonal Antibody to CtBP1 (Phospho-Ser422)
货号：
P40496
别名：
CTBP; C-terminal binding protein 1; EC 1.1.1;
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q13363
规格：
目录价
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Description |
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This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471(1995)Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787(1999)The MGC Project Team, Genome Res. 14:2121-2127(2004) |
Specification |
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|---|---|
| Aliases | CTBP; C-terminal binding protein 1; EC 1.1.1; |
| Entrez GeneID | 1487; |
| Swissprot | Q13363 |
| WB Predicted band size | 48kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of Serine 422(A-P-S(p)-P-G) derived from Human CtBP1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from Jurkat cells treated with TNF using CtBP1 (Phospho-Ser422) Antibody P40496.The lane on the right is treated with the antigen-specific peptide.
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Immunohistochemical analysis of paraffin-embedded human brain tissue, using CtBP1 (Phospho-Ser422) antibody P40496 (left)or the same antibody preincubated with blocking peptide (right).
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