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Rabbit Polyclonal Antibody to YB1 (Phospho-Ser102)
货号: P40518
别名: CBF-A; NSEP1; EFI-A; MSY-1; YBX1
应用: WB
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: P67809
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Description

YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs). Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A)n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP.Sakura H., Gene 73:499-507(1988)Didier D.K. Proc. Natl. Acad. Sci. U.S.A. 85:7322-7326(1988)Kolluri R., Nucleic Acids Res. 19:4771-4771(1991)

Specification

Aliases CBF-A; NSEP1; EFI-A; MSY-1; YBX1
Entrez GeneID 4904;
Swissprot P67809
WB Predicted band size 36kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around phosphorylation site of Serine 102(L-R-S(p)-V-G) derived from Human YB1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
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