Rabbit Polyclonal Antibody to Abl (Phospho-Tyr204)
货号：
P40543
别名：
p150; c-ABL; EC 2.7.10.2;
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P00519
规格：
目录价
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Description |
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Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 (involved in branch formation); ANXA1 (involved in membrane anchoring); DBN1, DBNL, CTTN, RAPH1 and ENAH (involved in signaling); or MAPT and PXN (microtubule-binding proteins). |
References |
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| Meyn MA, et al. (2006) J Biol Chem 281, 30907-16 Steen H, et al. (2003) Mol Cell Proteomics 2, 138-45 Salomon AR, et al. (2003) Proc Natl Acad Sci U S A 100, 443-8 |
Specification |
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|---|---|
| Aliases | p150; c-ABL; EC 2.7.10.2; |
| Entrez GeneID | 25; |
| Swissprot | P00519 |
| WB Predicted band size | 135kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 204 (K-L-Y(p)-V-S) derived from Human c-Abl. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/1000 |
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