Rabbit Polyclonal Antibody to CDC25B (Phospho-Ser353)
货号：
P40586
别名：
CDC25M2; MPIP2; Dual specificity phosphatase Cdc25B; CDC25HU2;
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P30305
规格：
目录价
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Description |
|---|
Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. Reboutier D, et al. (2012) J Cell Biol 197, 19-26 Lobjois V, et al. (2011) Biochem Biophys Res Commun 410, 87-90 Feng C, et al. (2007) Biol Reprod 77, 560-8 |
Specification |
|
|---|---|
| Aliases | CDC25M2; MPIP2; Dual specificity phosphatase Cdc25B; CDC25HU2; |
| Entrez GeneID | 994; |
| Swissprot | P30305 |
| WB Predicted band size | 64kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around phosphorylation site of serine 353(R-R-S(p)-V-T) derived from Human CDC25B . |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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