Rabbit Polyclonal Antibody to EPHA7 (Phospho-Tyr791)
货号：
P40534
别名：
EHK3; EK11; HEK11;
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q15375
规格：
目录价
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Description |
|---|
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. Fox G.M., Oncogene 10:897-905(1995)Mungall A.J., Nature 425:805-811(2003) |
Specification |
|
|---|---|
| Aliases | EHK3; EK11; HEK11; |
| Entrez GeneID | 2045; |
| Swissprot | Q15375 |
| WB Predicted band size | 112kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 791 (A-V-Y(p)-T-T) derived from Human EPHA7 . |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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