Rabbit Polyclonal Antibody to VAV3 (Phospho-Tyr173)
货号：
P40529
别名：
VAV3; FLJ40431; Guanine nucleotide exchange factor VAV3;
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9UKW4
规格：
目录价
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Description |
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This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.Trenkle T., Nucleic Acids Res. 26:3883-3891(1998)Movilla N., Mol. Cell. Biol. 19:7870-7885(1999) |
Specification |
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|---|---|
| Aliases | VAV3; FLJ40431; Guanine nucleotide exchange factor VAV3; |
| Entrez GeneID | 10451; |
| Swissprot | Q9UKW4 |
| WB Predicted band size | 100kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 173 (E-V-Y(p)-E-D) derived from Human VAV3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/1000 |
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