Rabbit Polyclonal Antibody to ATF1 (Phospho-Ser63)
货号：
P40553
别名：
ATF1; Activating transcription factor 1; Cyclic-AMP-dependent transcription factor ATF-1; TCR-ATF1; TREB36 protein
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P18846
规格：
目录价
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Description |
|---|
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. Mackenzie KF, et al. (2013) J Immunol 190, 565-77 Dickinson RJ, et al. (2011) J Biol Chem 286, 38018-26 Wang J, Zhou JY, Wu GS (2011) J Biol Chem 286, 22384-92 |
Specification |
|
|---|---|
| Aliases | ATF1; Activating transcription factor 1; Cyclic-AMP-dependent transcription factor ATF-1; TCR-ATF1; TREB36 protein |
| Entrez GeneID | 466; |
| Swissprot | P18846 |
| WB Predicted band size | 29kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around phosphorylation site of serine 63(R-P-S(p)-Y-R) derived from Human ATF1 . |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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