Rabbit Polyclonal Antibody to IKK- alpha/ beta (Phospho-Ser180/181)
货号：
P40569
别名：
FLJ40509; I-kappa-B kinase; IKBKB; kinase beta; NFKBIKB
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O15111
规格：
目录价
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Description |
|---|
Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.Hafeez BB, et al. (2008) Cancer Res 68, 8564-72 Cahill CM, Rogers JT (2008) J Biol Chem 283, 25900-12 Encinas M, et al. (2008)Cell Death Differ 15, 1510-21 |
Specification |
|
|---|---|
| Aliases | FLJ40509; I-kappa-B kinase; IKBKB; kinase beta; NFKBIKB |
| Entrez GeneID | 1147; |
| Swissprot | O15111 |
| WB Predicted band size | 85kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of serine 180/181 (C-T-S(p)-F-V) derived from Human IKK- alpha/ beta. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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