Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.Allen D, Fakler B, Maylie J, Adelman JP (2007) J Neurosci 27, 2369-76 Arrigoni G, et al. (2004) Biochemistry 43, 12788-98 Greif DM, Sacks DB, Michel T (2004) Proc Natl Acad Sci U S A 101, 1165-70