Rabbit Polyclonal Antibody to ADAM 17 (Phospho-Thr735)
货号：
P40657
别名：
CSVP, TACE, NISBD, ADAM18, CD156B
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P78536
规格：
目录价
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Description |
|---|
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Also involved in the activation of Notch pathway. |
Specification |
|
|---|---|
| Aliases | CSVP, TACE, NISBD, ADAM18, CD156B |
| Entrez GeneID | 6868; |
| Swissprot | P78536 |
| WB Predicted band size | 93kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of Threonine 735 (P-Q-T(p)-P-G) derived from Human ADAM 17. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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