Mouse Monoclonal Antibody to KMT2D
货号：
31725
别名：
ALR; KMS; MLL2; MLL4; AAD10; KABUK1; TNRC21; CAGL114
应用：
IHC,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O14686
规格：
目录价
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Description |
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The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. |
References |
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| 1.Clin Lung Cancer. 2018 Jul;19(4):e489-e501. 2.J Cancer Res Clin Oncol. 2018 Jun;144(6):1025-1035. |
Specification |
|
|---|---|
| Aliases | ALR; KMS; MLL2; MLL4; AAD10; KABUK1; TNRC21; CAGL114 |
| Entrez GeneID | 8085 |
| Swissprot | O14686 |
| clone | 1D10F6 |
| WB Predicted band size | 593kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human KMT2D (AA: 445-599) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Flow cytometric analysis of Hela cells using KMT2D mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using KMT2D mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using KMT2D mouse mAb with DAB staining.
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