Rabbit Polyclonal Antibody to AurB/C (Phospho-Thr236/202)
货号:
P40716
别名:
AIE1; AIE2; AURKC; Aurora-C; Aurora/Ipl1-related kinase 3; Aurora/Ipl1/Eg2 protein 1; Aurora/Ipl1/Eg2 protein 2; EC 2.7.11.1; STK13; STKD; Serine/threonine protein kinase 13; kinase AIK3
应用:
IHC
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q9UQB9
规格:
目录价
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Description |
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Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'. |
Specification |
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|---|---|
| Aliases | AIE1; AIE2; AURKC; Aurora-C; Aurora/Ipl1-related kinase 3; Aurora/Ipl1/Eg2 protein 1; Aurora/Ipl1/Eg2 protein 2; EC 2.7.11.1; STK13; STKD; Serine/threonine protein kinase 13; kinase AIK3 |
| Entrez GeneID | 6795; |
| Swissprot | Q9UQB9 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of threonine 236/202 (C-G-T(p)-L-D) derived from Human AurB/C. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| IHC | 1/50-1/100 |


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