Rabbit Polyclonal Antibody to MAX(Phospho-Ser11)
货号:
P40766
别名:
MAX;bHLHd4
应用:
WB
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P61244
规格:
目录价
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Description |
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The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. |
Specification |
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Aliases | MAX;bHLHd4 |
Entrez GeneID | 4149 |
Swissprot | P61244 |
WB Predicted band size | 21kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | A synthetic phosphorylated peptide around S11 of human MAX (NP_002373.3). |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
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WB | 1/500-1/2000 |