Rabbit Polyclonal Antibody to WAVE1 (Phospho-Tyr125)
货号:
P40761
别名:
KIAA0269; SCAR1; Verprolin homology domain-containing protein 1; WAS1; WASF1; WASP-family protein member 1; Wiskott-Aldrich syndrome protein family member 1
应用:
WB,IHC
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
Q92558
规格:
目录价
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Description |
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Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. |
Specification |
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Aliases | KIAA0269; SCAR1; Verprolin homology domain-containing protein 1; WAS1; WASF1; WASP-family protein member 1; Wiskott-Aldrich syndrome protein family member 1 |
Entrez GeneID | 8936; |
Swissprot | Q92558 |
WB Predicted band size | 70kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Peptide sequence around phosphorylation site of tyrosine 125 (E-T-Y(p)-D-V) derived from Human WAVE1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from NIH/3T3 cells, treated with Insulin (0.01U/ml, 15mins), using WAVE1 (Phospho-Tyr125) antibody P40761. The lane on the right is treated with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using WAVE1 (Phospho-Tyr125) antibody P40761. The picture on the right is treated with the synthesized peptide.