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Mouse Monoclonal Antibody to CASP6
货号: 31731
别名: MCH2
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P55212
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Description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.

References

1.Biochemistry. 2017 Aug 29;56(34):4568-4577.
2.Acta Neuropathol Commun. 2016 Dec 8;4(1):127.

Specification

Aliases MCH2
Entrez GeneID 839
Swissprot P55212
clone 3B7C3
WB Predicted band size 33.3kDa
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CASP6 (AA: 194–293) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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