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Mouse Monoclonal Antibody to ATG10
货号: 31729
别名: APG10; APG10L; pp12616
应用: WB,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q9H0Y0
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Description

Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).

References

1.Int J Cancer. 2016 Oct 1;139(7):1564-73.
2.PLoS One. 2012;7(12):e52705.

Specification

Aliases APG10; APG10L; pp12616
Entrez GeneID 83734
Swissprot Q9H0Y0
clone 8A9B3
WB Predicted band size 25.3kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human ATG10 (AA: 1-125) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
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